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Intestinal and multivisceral transplantation

Intestinal and multivisceral transplantation

Small intestine transplantation is indicated in patients with irreversible intestinal failure who are dependent on parenteral nutrition. Intestinal failure is understood as the inability of the intestine to ensure sufficient nutrition, and water and mineral metabolism of the patient. Loss of the small intestine is the most common cause of intestinal failure. Other causes may include serious functional disorders. Life-threatening complications of parenteral nutrition are the most common reasons for transplantation.

Based on the range of involvement, either isolated transplantation of the small intestine is done, or combined transplantation of the small intestine and the liver, which is damaged due to long-term parenteral nutrition. In some indications of an extensive involvement, multivisceral transplantation is performed; in addition to the small intestine and the liver, the stomach and the duodenum with the pancreas are transplanted.

Patients are usually referred for an assessment by their treating doctor of the nutritional outpatient office.

Patient documentation should be sent in advance before the assessment, including previous surgeries and performed imaging assessments. If a patient is considered as a suitable candidate for small intestine transplantation, detailed assessments are scheduled in advance, which are done during short-term hospitalisation at our unit.

Transplantation team:

doc. Jiří Froněk, Ph.D. FRCS
MUDr. Libor Janoušek, Ph.D.
doc. MUDr. Martin Oliverius, Ph.D. FEBS
MUDr. Michal Kudla, Ph.D.

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