Na titulní stránku Cevkoon Na titulní stránku IKEM
Oddělení experimentální
hypertenze a nefrologie
Oddělení experimentální
kardiologie
Oddělení experimentálního
výzkumu náhrad
orgánových funkcí

Publikace vzniklé v rámci projektu CEVKOON

39. Acute live failure by thioacetamide: selection of optimal dosage in Wistar and Lewis rats. Koblihová E, Mrázová I, Vernerová Z, Ryska M. Physiol Res. 63: 491-503, 2014. MZUP 8/5
38. Hepatocyte transplantation attenuates the course of acute liver failure induced by thioacetamide in Lewis rats. Koblihová E, Lukšan O, Mrázová I, Ryska M, Červenka L. Physiol Res. 2015 Mar 24.MZUP 9/5
37. Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis. Sticova E, Lodererova A, van de Steeg E, Frankova S, Kollar M, Lanska V, Kotalova R, Dedic T, Schinkel AH, Jirsa M. Int J Clin Exp Pathol. 2015 May 1;8(5):5252-62. IF (2014) = 1,891. MZUP 10/5
36. Inhibition of soluble epoxide hydrolase counteract the development of renal dysfunction and progression of congestive heasr failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula. Červenka L, Melenovský V, Husková Z, Škaroupková P, Nishiyama A, Sadowski J. Clin Exp Pharmaco. Physiol. 2015 Jul;42(7):795-807. MZUP 4/5
35. Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula. Červenka L, Melenovský V, Husková Z, Sporková A, Bürgelová M, Škaroupková P, Hwang SH, Hammock BD, Imog JF, Sadowski J. Physiol Res 2015 Jun 5. MZUP 5/5
34. Intrapulmonary activation of the angiotensin-converting enzyme type 2/angiotensin 1-7/G-protein-coupled Mas receptor axis attenuates pulmonary hypertension in Ren-2 transgenic rats exposed to chronic hypoxia. Hampl V, Herget J, Bíbová J, Baňasová A, Husková Z, Vaňourková Z, Jíchová Š, Kujal P, Vernerová Z, Sadowski J, Červenka L. Phys Res. 64; 25-38, 2015. MZUP 3/5
33. Combined suppression of the intrarenal and circulating vasoconstrictor renin-ACE-ANG II axis and augmentation of the vasodilator ACE2-ANG 1-7-Mas axis attenuates the systemic hypertension in Ren-2 transgenic rats exposed to chronic hypoxia. Červenka L, Bíbová J, Husková Z, Vaňourková Z, Kramer HJ, Herget J, Jíchová Š, Sadowski J, Hampl V. Phys Res. 64:11-24, 2015. MZUP 2/5
32. Addition of ETA receptor blockade increases renoprotection provided by renin-angiotensin system blockade in 5/6 nephrectomized Ren-2 transgenic rats. Čertíková Chábová V, Vernerová Z, Kujal P, Husková Z, Škaroupková P, Tesař V, Kramer HJ, Kompanovska-Jezierska E, Walkowska A, Sadowski J, Červenka L, Vaněčková I. Life Sci. 118 (2014); 297-305. MZUP 1/5
31. Left Atrial Remodeling and Function in Advanced Heart Failure With Preserved or Reduced Ejection Fraction. Vojtech Melenovsky, Seok-Jae Hwang, Margaret M. Redfield, Rosita Zakeri, Grace Lin, Barry A. Borlaug. Circulation Heart Failure 2015 Mar;8(2):295-303. MZUP 7/5
30. Right heart dysfunction in heart failure with preserved ejection fraction. Vojtech Melenovsky, Seok-Jae Hwang, Grace Lin, Margaret M. Redfield and Barry A. Borlaug. European Heart Journal 2014 Dec 21;35(48):3452-62. MZUP 6/5 (chybí poděkování)
29. Reverse Endoventricular artificial obturator in tricuspid valve position. Experimental feasibility research study. Šochman J, Peregrin JH, Pavcnik D, Uchida BT, Timmermans HA, Sedmera D, Benada O, Kofronova O, Keller FS, Rosch. J. Phys. Res. 63: 157-165, 2014. MZUP 6/4
28. Ventricular assist devices in heart failure: how to support the heart but prevent atrophy? Pokorný M, Červenka L, Netuka I, Pirk J, Koňařík M, Malý J. Phys Res. 63: 147-156, 2014. MZUP 2/4
27. Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Kujal P, Čertíková Chábová V, Škaroupková P, Husková Z, Vernerová Z, Kramer HJ, Walkowska A, Kompanovska-Jezierska E, Sadowski J, Kitada K, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Červenka L. Clin. Exp. Pharmacol. Physiol. 41: 227-237, 2014. MZUP 1/4
26. Menopausal transition enhances the atherogenic risk of smoking in middle aged women. Pitha J, Kralova Lesna I, Sekerova A, Poledne R, Kovar J, Lejskova M, Dvorakova H, Adamkova S, Lanksa V, Bobak M. Int. J. Cardiol. 168: 190-196, 2013. MZUP 5/4
25. Relationships Between Right Ventricular Function, Body Composition, and Prognosis in Advanced Heart Failure. Melenovsky V, Kotrc M, Borlaug BA, Marek T, Kovar J, Malek I, Kautzner J. J.Am.Coll.Cardiol.62.No18:1660-1670, 2013. MZUP 4/4
24. Isolated X-Linked Hypertrophic Cardiomyopathy Caused by a Novel Mutation of the Four-and-a-Half LIM Domain 1 Gene. Hartmannova H, Kubanek M, Sramko M, Piherova L, Noskova L, Hodanova K, Stranecky V, Pristoupilova A, Sovova J, Marek T, Maluskova J, Ridzon P, Kautzner J, Hulkova H, Kmoch S. Circ.-Cardiovasc.Genet 6:543-551,2013. MZUP 3/4
23. Metabolic characterization of volume overload heart failure due to aorto-caval fistula in rats. Melenovský V, Beneš J, Škaroupková P, Sedmera D, STrnad H, Kolář M, Vlček C, Petrák J, Beneš J, Papoušek F, Oliyarnyk O, Kazdová L, Červenka L. Mol. Cell. Biochem. 354: 83-96, 2011. MZUP 5/1 (chybí poděkování)
22. Assessment of optimal right ventricular pacing site using invasive measurement of left ventricular systolic and diastolic function. Vlastimil Vancura, Dan Wichterle, Vojtech Melenovsky, and Josef Kautzner Europace doi:10.1093/europace/eut068
22. Assessment of optimal right ventricular pacing site using invasive measurement of left ventricular systolic and diastolic function. Vlastimil Vancura, Dan Wichterle, Vojtech Melenovsky, and Josef Kautzner Europace doi:10.1093/europace/eut068
21. Associations Between Cardiac Fibrosis and Permanent Atrial Fibrillation in Advanced Heart Failure. B. ALDHOON, T. KUČERA, N. SMORODINOVÁ, J. MARTÍNEK, V. MELENOVSKÝ, J. KAUTZNER PHYSIOLOGICAL RESEARCH • ISSN 0862-8408 (print) • ISSN 1802-9973 (online)
20. Resting Heart Rate and Heart Rate Reserve in Advanced Heart Failure Have Distinct Pathophysiologic Correlates and Prognostic Impact. Jan Benes, MD, Martin Kotrc, MD, Barry A. Borlaug, MD,x Katerina Lefflerova, MD, PHD, Petr Jarolim, MD, PHD,z Bela Bendlova, PHD,y Antonin Jabor, MD, PHD, Josef Kautzner, MD, PHD, Vojtech Melenovsky, MD, PHD JACC: Heart Failure Vol. 1, No. 3, 2013 June 2013:259–66.
19. Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME. Honetschlagerová Z, Kitada K, Husková Z, Sporková A. Kopkan L, Bürgelová M, Varcabová Š, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kujal P, Vernerová Z, Červenka L. J Hypertens.31: 321-332, 2013.
18. Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system. Varcabová Š, Husková Z, Kramer HJ, Hwang HS, Hammock BD, Imig JD, Kitada K, Červenka L. Clin Exp Pharmacol Physiol. 40: 273-281, 2013.
17. Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension. Kopkan L, Husková Z, Sporková A, Varcabová Š, Honetschlagerová Z, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Kramer HJ, Bürgelová M, Vojtíšková A, Kujal P, Vernerová Z, Červenka L. Kidney and Blood Press Res. 35: 595-607, 2012.
16. The impact of left ventricle assist device on circulating endothelial microparticles – pilot study. Pitha J, Dorazilova Z, Melenovsky V. Kralova Lesna I, Stavek P, Stepankova J, Urban M, Maly J, Netuka I. Neuro Endorcion Lett. 2012; 33 (Suppl. 2): 68-72.
15. Availability of energetic substrates and exercise performance in heart failure with or without diabetes. Melenovsky V, Kostr M, Polak J, Pelikanova T, Bendlova B, Cahova M, Malek I, Jarolim P, Kazdova L, Kautzner J. Eur J Heart Fail. 2012; 14: 754-763.
14. The effects of phosphodiesterase 5 inhibition on hemodynamics, functional status and survival in advanced heart failure and pulmonary hypertension: a case-control study Adrian Reichenbach, MD; Hikmet Al-Hiti, MD, PhD; Ivan Malek, assoc. prof., MD, PhD; Jan Pirk, Prof., MD, PhD; Eva Goncalvesova, assoc. prof., MD, PhD; Josef Kautzner, Prof., MD, PhD; Vojtech Melenovsky International Journal of Cardiology
13. Effects of combined endothelin a receptor and Renin-Angiotensin system blockade on the course of end-organ damage in 5/6 nephrectomized ren-2 hypertensive rats. Vaněčková I, Kujal P, Husková Z, Vaňourková Z, Vernerová Z, Certíková Chábová V, Skaroupková P, Kramer HJ, Tesař V, Cervenka L. Kidney Blood Press Res. 2012;35(5):382-92. Epub 2012 Apr 4.
12. Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-1-ylureido)cyclohexyl-oxy]benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension. Neckář J, Kopkan L, Husková Z, Kolář F, Papoušek F, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Malý J, Netuka I, Ošťádal B, Červenka L.v Clin Sci (Lond). 2012 Jun;122(11):513-25.
11. The course of heart failure development and mortality in rats with volume overload due to aorto-caval fistula. Melenovsky V, Skaroupkova P, Benes J, Torresova V, Kopkan L, Cervenka L. Kidney Blood Press Res. 2012;35(3):167-73. Epub 2011 Nov 24.
10. Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets - monoamine oxidase A and transglutaminase 2. Petrak J, Pospisilova J, Sedinova M, Jedelsky P, Lorkova L, Vit O, Kolar M, Strnad H, Benes J, Sedmera D, Cervenka L, Melenovsky V. Proteome Sci. 2011 Nov 11;9(1):69.
9. Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats. Honetschlägerová Z, Sporková A, Kopkan L, Husková Z, Hwang S8_Sporkova2011.pdfH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, Chábová VC, Tesař V, Cervenka L. J Hypertens. 2011 Aug;29(8):1590-601.
8. Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats. Sporková A, Kopkan L, Varcabová S, Husková Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Cervenka L. Am J Physiol Regul Integr Comp Physiol. 2011 Jun;300(6):R1468-75. Epub 2011 Mar 16.
7. Effect of metformin therapy on cardiac function and survival in a volume-overload model of heart failure in rats. Benes J, Kazdova L, Drahota Z, Houstek J, Medrikova D, Kopecky J, Kovarova N, Vrbacky M, Sedmera D, Strnad H, Kolar M, Petrak J, Benada O, Skaroupkova P, Cervenka L, Melenovsky V. Clin Sci (Lond). 2011 Jul;121(1):29-41.
6. Castration has antihypertensive and organoprotective effects in male but not in female heterozygous Ren-2 rats. Vaněčková I, Husková Z, Vaňourková Z, Cervenka L. Kidney Blood Press Res. 2011;34(1):46-52. Epub 2010 Dec 17.
5. Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension. Honetschlägerová Z, Z Husková Z, Vaňourková Z, Sporková A, Kramer HJ, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Červenka L, Kopkan L. J Physiol. 2011 Jan 1;589(Pt 1):207-19.
4. Knockout of angiotensin 1-7 receptor Mas worsens the course of two-kidney, one-clip Goldblatt hypertension: roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II. Rakušan D, Bürgelová M, Vaněčková I, Vaňourková Z, Husková Z, Skaroupková P, Mrázová I, Opočenský M, Kramer HJ, Netuka I, Malý J, Alenina N, Bader M, Santos RA, Cervenka L. Kidney Blood Press Res. 2010;33(6):476-88. Epub 2010 Nov 10.
3. Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects? Kujal P, Chábová VČ, Vernerová Z, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Vaňourková Z, Husková Z, Opočenský M, Skaroupková P, Schejbalová S, Kramer HJ, Rakušan D, Malý J, Netuka I, Vaněčková I, Kopkan L, Cervenka L. Clin Exp Pharmacol Physiol. 2010 Dec;37(12):1159-69.
2. High-salt intake enhances superoxide activity in eNOS knockout mice leading to the development of salt sensitivity. Kopkan L, Hess A, Husková Z, Cervenka L, Navar LG, Majid DS. Am J Physiol Renal Physiol. 2010 Sep;299(3):F656-63. Epub 2010 Jul 7.
1. N-acetylcysteine attenuates iodine contrast agent-induced nephropathy in 5/6-nephrectomized rats. Sochman J, Peregrin JH, Bürgelová M, Kopkan L, Kramer HJ, Cervenka L. Kidney Blood Press Res. 2010;33(2):149-56. Epub 2010 May 26.